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The PROUD Study


Examining the impact on gay men of using Pre-Exposure Prophylaxis (PrEP)


What is PrEP?


PrEP (Pre-Exposure Prophylaxis) is a new way to reduce the risk of getting HIV. It involves HIV negative people taking a daily tablet that contains drugs commonly used to treat HIV.

PROUD is a two-year study to recruit volunteers across England, who will be placed at random into one of two groups. One group will use PrEP from the start of the study, and the other group will receive PrEP after 12 months.

Truvada (which contains tenofovir and emtricitabine, also called FTC) is used in this study. Truvada is already widely used and any side effects are usually mild.

Previous studies with gay men found that using PrEP almost halved HIV infections – and there were even fewer infections amongst men who took their pill every day.

Volunteer to take part in the study


  • Are you a gay or bisexual man?
  • Have you recently had sex without a condom?
  • Are you willing to take part in research that aims to reduce your risk of HIV?

Participation is straightforward and won’t take much of your time. Click here to find out more about Volunteering.

News

 

PROUD Pilot Study Update

 

PROUD pilot study

The PROUD Trial Steering Committee (TSC) supported the Trial Management Group’s (TMG) request to submit an application for funding for a full PROUD trial of PrEP among gay men and other men who have sex with men in the UK. An application was submitted to the UK National Institute of Health Research (NIHR), Health Technology Assessment (HTA) researcher led call on 6th January 2014.

Read more

Latest News

All the study spaces are now filled!

Thank you to all those who have enrolled, the study teams and the community organisations who have worked together to achieve this.

Watch this space for updates – we have applied for additional funding to expand and if successful hope to reopen study recruitment early in 2015.

Meanwhile, some participating clinics are keeping a register of people interested in PrEP so they can let you know if recruitment reopens.

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Trial participants can now use a mobile format to complete their diary and questionnaires.            This can be found at https://ctuapps.ctu.mrc.ac.uk/
ProudMobile

HIV charities release joint statement on PrEP

A group of the UK’s leading HIV charities have released a joint statement outlining their position on Pre-Exposure Prophylaxis (PrEP). [read more]

Recruitment

Recruitment has been running since November 2012 and 550 men have been recruited from the UK clinics listed below.

Latest update

Accruals

Updated status as at 10th April 2014.

550

The PROUD study has recruited in:

  • London (8 sites)
  • Brighton
  • Birmingham
  • York
  • Manchester
  • Sheffield

For participating clinic address/contact information, please [click here].